The Yin and Yang of Managing Competing and Conflicting Interests in Research

The Yin and Yang of Managing Competing and Conflicting Interests in Research

Welcome and Introduction:

Fei-Fei Liu, MD, FRCPC
Chief of Radiation Medicine Program and Head of the Department of Radiation Oncology, Princess Margaret Cancer Centre
Senior Scientist, Princess Margaret Cancer Centre Research Institute
Professor and Chair of the Department of Radiation Oncology, University of Toronto
Dr. Mariano Elia Chair in Head & Neck Cancer Oncology, University of Toronto/Princess Margaret Cancer Centre

Dr. Fei-Fei Liu’s research program is focused on investigating and developing novel molecular therapeutic strategies for human malignancies, delivered in conjunction with radiation therapy, along with investigating molecular aberrancies for several human cancers including breast, cervix, nasopharyngeal, and head/neck cancers. Dr. Liu has over 170 peer-reviewed publications on these topics, and has filed three patents. She currently holds peer-reviewed research funding from agencies including the Canadian Institutes of Health Research (CIHR) and the Canadian Cancer Society Research Institute (CCSRI). She is also the founding Director of a $1.9M Terry Fox Foundation Research Training Initiative, entitled “Strategic Training in Transdisciplinary Radiation Science for the 21st Century (STARS21)”, with the objective to train the next generation of trans-disciplinary scientists in Radiation Medicine.  Lastly, her studies also focus on a major clinical issue with radiation therapy, radiation fibrosis, which is an irreversible scarring of normal tissues that can result in significant functional morbidity. Her team is interested in understanding how adipose-derived stem cells may aid in tissue regeneration after treatment with ionizing radiation.

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Speakers:

Zubin Master, PhD
Associate Consultant II, Biomedical Ethics Research Program, Mayo Clinic

Zubin Master, PhD is an Associate Consultant II in the Biomedical Ethics Research Program at Mayo Clinic. Previously, he was an Associate Professor at the Alden March Bioethics Institute of Albany Medical College, Research Associate for University of Alberta’s Health Law Institute, and has held adjunct or visiting professor appointments at the University of Montreal, the National Institute of Environmental Health Sciences of the National Institutes of Health, and the Ottawa Hospital Research Institute. Prior to leaving public service, Dr. Master worked as a Senior Policy Advisor at Health Canada where he led the development of Health Canada’s Scientific Integrity Framework and developed regulations under the Assisted Human Reproduction Act. He holds an undergraduate degree in genetics from York University, a PhD in cellular and molecular biology from the University of Toronto, and completed post-doctoral fellowships in bioethics and health policy at Dalhousie University and the University of British Columbia. His research interests focus on ethics and policy of research specializing in stem cell research, biobanking, and the responsible conduct of research including authorship and publication, mentorship and peer review among other areas. Dr. Master serves on several committees and journal editorial boards and has published over 70 articles.

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Paula Rochon, MD, MPH, FRCPC
Vice President, Research, Women's College Hospital
Senior Scientist, Women’s College Research Institute
Professor, Department of Medicine and Institute of Health Policy, Management & Evaluation, University of Toronto
Senior Scientist, Institute for Clinical Evaluative Sciences
Retired Teachers of Ontario Chair in Geriatric Medicine, University of Toronto​

Dr. Paula Rochon is a geriatrician and health services researcher. Her research focuses on understanding the unique needs of older adults, most of whom are women. Much of her clinical work as a geriatrician in conjunction with her extensive research has laid the foundation of her expertise on older adults. She is one of the leading Canadian health-services researchers in geriatric medicine. In particular, her research explores how to promote health in older adults. Her work has contributed substantively to three areas of focus that affect individual patients and healthcare systems: the need for evidence to provide information that is more relevant to women and men, the exploration of strategies to reduce adverse drug events and to optimize drug therapy, and specifically the impact of widespread use of antipsychotic therapy in older people. She has a strong record of funding from federal funding agencies and more than 200 published papers in peer-reviewed journals. In July 2015, she was appointed as the inaugural Retired Teachers of Ontario Chair in Geriatric Medicine at the University of Toronto.

Dr. Rochon is the lead of Women’s Xchange, which is a women’s health knowledge translation and exchange centre based at Women’s College Hospital. Women’s Xchange promotes sex and gender considerations in research through a consultation service, builds the capacity of researchers in women’s health, drives community-engaged research and promotes knowledge translation.

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Brian C. Martinson, PhD
Senior Research Investigator, HealthPartners Institute
Research Scientist, Center for Chronic Disease Outcomes Research, Minneapolis VA
Associate Professor of Medicine, University of Minnesota

Brian C. Martinson earned his PhD in sociology and demography at the University of Wisconsin–Madison, and received postdoctoral training in cardiovascular behavioral health at the University of Minnesota, Minneapolis. He is a Senior Research Investigator at HealthPartners Institute, Core Investigator at the Minneapolis VA, Center for Chronic Disease Outcomes Research, and Associate Professor, University of Minnesota, Department of Medicine. Over the past 15 years, Dr. Martinson has contributed both substantively and methodologically to improving the understanding of research related behavior (both that which contributes to research integrity and that which can undermine it), as well as to understanding the determinants of such behavior. He has led or co-led four federally funded research projects on these topics (R01NR08090; R01NS052885; R21RR025279, I01HX001120). In 2009–2010, Dr. Martinson served on an invited expert panel on research integrity, convened by the Council of Canadian Academies at the request of Industry Canada, leading to the report, Honesty, Accountability and Trust: Fostering Research Integrity in Canada.  In 2014, he served on the planning committee and subsequently as a speaker at a workshop of the Roundtable on Science and Welfare in Laboratory Animal Use (An ILAR Roundtable Series) – The Missing "R": Reproducibility in a Changing Research Landscape, National Academy of Sciences, Institute for Laboratory Animal Research. Washington, D.C., June 4-5. He served as a member of the authoring panel of the 2017 National Academies of Sciences report, Fostering Integrity in Research.

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Susan Zimmerman
Executive Director, Secretariat on Responsible Conduct of Research

Susan Zimmerman is the Executive Director of the Secretariat on Responsible Conduct of Research (SRCR) in Ottawa. SRCR is responsible for the implementation of the Tri-Agency Framework on Responsible Conduct of Research on behalf of the Canadian Institutes of Health Research (CIHR), the Natural Sciences and Engineering Research Council of Canada (NSERC) and the Social Sciences and Humanities Research Council of Canada (SSHRC). The Secretariat is also responsible for the Tri-Council Policy Statement: Ethical Conduct for Research Involving Humans.

Ms. Zimmerman is a lawyer whose career has focused on health law and public policy. A native of Montreal, she received her undergraduate degree from Bryn Mawr College, civil law and common law degrees from McGill University, and a Master of Laws from the University of Toronto. Her professional experience includes positions as a senior research associate at the Centre for Medicine, Ethics and Law at McGill University, Director of Legislation and Law Reform at the Canadian Bar Association, legal counsel at Health Canada and Director of Research for the Law Commission of Canada. Prior to her appointment to the Secretariat in September, 2007, Ms Zimmerman was a member of the Health Law Group at the Toronto office of a national law firm, where she represented health care institutions and a variety of health care professionals.

She has also been a university lecturer in health law and ethics and a member of research ethics boards.

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The Yin and Yang of Managing Competing and Conflicting Interests in Research​

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Retired Teachers of Ontario Chair in Geriatric Medicine, University of Toronto​

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